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Latest thinking in Barrett's esophagus: Heading off esophageal cancer
In some patients, persistent GERD also stimulates immature progenitor cells in the distal esophagus to differentiate into intestinal cell types that constitute the specialized intestinal metaplasia characteristic of Barrett's esophagus. The metaplasia that occurs in Barrett's esophagus may thus represent an adaptive substitution of cells that are highly sensitive to peptic acid injury to cells that are better able to withstand it. Unfortunately, the metaplastic cells are predisposed to malignancy.
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Melanoma gene test benefits select patients
Las Vegas — While genetic testing for melanoma remains controversial in the clinical setting, one expert says that when done properly, it can empower patients without creating risks.
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New leukemia agent paves way for transplants
A new treatment option for treating T-cell lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL) is on the horizon. In 2006, GlaxoSmithKline will begin marketing the recently approved nelarabine (Arranon), a water-soluble pro-drug of the cytotoxic deoxyguanosine analog 9-β-D-arabinofuranosylguanine (ara-G).
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Low fat diet may help prevent breast cancer
A low-fat diet probably does help reduce the risk of breast cancer, according to a lead researcher for the Women's Health Initiative (WHI) dietary modification trial.
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