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Immune targets in cancer treatment
With an increasing understanding of the role of immunological targets in cancer treatment, J.C. Becker, M.D., of the University of Wurzburg, Germany, is currently investigating the role of several T-cell antigens including IAP, survivin and BCL2 families and their roles in apoptosis.
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Dermatology Case Challenge: Generalized hyperkeratosis in a very sick man
An 84-year-old man presents with pruritic, generalized, erythematous and crusted hyperkeratotic dermatitis. The patient's history is remarkable for laryngeal cancer, chronic obstructive lung disease, chronic renal insufficiency, and long-term prednisone therapy for possible bullous pemphigoid. The photograph demonstrates an erythematous, tense skin surface with severe crusted hyperkeratosis on the patient's hand.
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Physician shares lessons on aphthosis
A fundamental lesson and one that has been a basis for years of continued research is that aphthosis is a multifactorial disease.
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Oncology and reconstruction
Skin cancer is on the rise, and surgical excision has been and remains the treatment of choice. Radiation is an option, but the inconvenience and inferior cosmetic results make it a less attractive option, according to Dr. Spencer. Radiation for any type of cancer produces changes in the appearance of skin that tend to worsen with time, including permanent loss of sweat glands, dyspigmentation and telangiectasias.
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